若你推介TRANSITIONS有人問你中國人食白米食了幾千年，你有什麼醫學研究證明吃白米不好，要吃你那個低升糖指數的食物，你可以如何回答？
其實Transitions健康人生模式計劃採用最新的科學資訊，並由醫生、研究員、博士和體適能專家組成的美國研究團隊研發而成。Transitions健康人生模式計劃研發團隊在體重管理、人體營養研究和成功系統的經驗累計超過一百年。
對於文章開始時的問題，下面的新聞已幫了你回答：
(法新社)2010年11月25日 星期四 12:05
（法新社華盛頓 24日電） 丹麥研究人員找出預防及治療肥胖的致勝食譜：攝取高蛋白質 ，並少吃精緻澱粉如白吐司和白米等。哥本哈根大學（University of Copenhagen）生命科學院研究人員，拿歐洲官方飲食建議，與近期強調以蛋白質和碳水化合物控制食慾的飲食結構兩相比較，研究人員總結，歐洲官方飲食建議「不足以預防肥胖」。這分代號為古希臘 哲學家「第歐根尼」（Diogenes）的專案研究，刊載於11月25日的新英格蘭 醫學期刊（New England Journal of Medicine）。第歐根尼崇尚自然的生活方式。研究報告聲明：「如果想減肥，飲食應該富含高蛋白質、多吃瘦肉、低脂乳製品和豆類，減少攝取精緻澱粉卡路里，如白吐司和精緻白米等。」報告說：「遵照此種飲食方式，可以吃到飽，不用記算卡路里，不必擔心體重上升問題。」（譯者：中央社陳禹安） 大家想看看那份報告的原文嗎？alex已經幫助大家找出來了，就在下面。有需要可以給你朋友令他們更有信心。
original article
The new england journal o f medicine
2102 n engl j med 363;22 nejm.org november 25, 2010
Diets with High or Low Protein Content and
Glycemic Index for Weight-Loss Maintenance
Thomas Meinert Larsen, Ph.D., Stine-Mathilde Dalskov, M.Sc.,
Marleen van Baak, Ph.D., Susan A. Jebb, Ph.D., Angeliki Papadaki, Ph.D.,
Andreas F.H. Pfeiffer, M.D., J. Alfredo Martinez, Ph.D.,
Teodora Handjieva-Darlenska, M.D., Ph.D., Marie Kunešová, M.D., Ph.D.,
Mats Pihlsgård, Ph.D., Steen Stender, M.D., Ph.D., Claus Holst, Ph.D.,
Wim H.M. Saris, M.D., Ph.D., and Arne Astrup, M.D., Dr.Med.Sc.,
for the Diet, Obesity, and Genes (Diogenes) Project
Abstract
Background
Studies of weight-control diets that are high in protein or low in glycemic index have
reached varied conclusions, probably owing to the fact that the studies had insufficient
power.
Methods
We enrolled overweight adults from eight European countries who had lost at least
8% of their initial body weight with a 3.3-MJ (800-kcal) low-calorie diet. Participants
were randomly assigned, in a two-by-two factorial design, to one of five ad libitum
diets to prevent weight regain over a 26-week period: a low-protein and low-glycemicindex
diet, a low-protein and high-glycemic-index diet, a high-protein and lowglycemic-
index diet, a high-protein and high-glycemic-index diet, or a control diet.
Results
A total of 1209 adults were screened (mean age, 41 years; body-mass index [the weight
in kilograms divided by the square of the height in meters], 34), of whom 938 entered
the low-calorie-diet phase of the study. A total of 773 participants who completed
that phase were randomly assigned to one of the five maintenance diets; 548 completed
the intervention (71%). Fewer participants in the high-protein and the lowglycemic-
index groups than in the low-protein–high-glycemic-index group dropped
out of the study (26.4% and 25.6%, respectively, vs. 37.4%; P = 0.02 and P = 0.01 for the
respective comparisons). The mean initial weight loss with the low-calorie diet was
11.0 kg. In the analysis of participants who completed the study, only the lowprotein–
high-glycemic-index diet was associated with subsequent significant weight
regain (1.67 kg; 95% confidence interval [CI], 0.48 to 2.87). In an intention-to-treat
analysis, the weight regain was 0.93 kg less (95% CI, 0.31 to 1.55) in the groups assigned
to a high-protein diet than in those assigned to a low-protein diet (P = 0.003) and
0.95 kg less (95% CI, 0.33 to 1.57) in the groups assigned to a low-glycemic-index
diet than in those assigned to a high-glycemic-index diet (P = 0.003). The analysis
involving participants who completed the intervention produced similar results. The
groups did not differ significantly with respect to diet-related adverse events.
Conclusions
In this large European study, a modest increase in protein content and a modest reduction
in the glycemic index led to an improvement in study completion and maintenance
of weight loss. (Funded by the European Commission; ClinicalTrials.gov
number, NCT00390637.)
From the Department of Human Nutrition,
Faculty of Life Sciences (T.M.L., S.-M.D.,
A.A.), and the Department of Clinical
Biochemistry, Gentofte Hospital (S.S.),
University of Copenhagen; and the Institute
of Preventive Medicine, Copenhagen
University Hospital (M.P., C.H.) — all in
Copenhagen; the NUTRIM (Nutrition and
Toxicology Research Institute Maastricht)
School for Nutrition, Toxicology and Metabolism,
Department of Human Biology,
Maastricht University Medical Centre,
Maastricht, the Netherlands (M.B.,
W.H.M.S.); the Medical Research Council
Human Nutrition Research, Elsie Widdowson
Laboratory, Cambridge, United Kingdom
(S.A.J.); the Department of Social
Medicine, Preventive Medicine, and Nutrition
Clinic, University of Crete, Heraklion,
Crete, Greece (A.P.); the Department of
Clinical Nutrition, German Institute of
Human Nutrition Potsdam-Rehbrücke,
Nuthetal, Germany (A.F.H.P.); the Department
of Endocrinology, Diabetes, and
Nutrition, Charité Universitätsmedizin
Berlin, Berlin (A.F.H.P.); the Department
of Physiology and Nutrition, University of
Navarra, Pamplona, Spain (J.A.M.); the
Department of Pharmacology and Toxicology,
Medical Faculty, National Transport
Hospital, Sofia, Bulgaria (T.H.-D.);
and the Obesity Management Center, Institute
of Endocrinology, Prague, Czech
Republic (M.K.). Address reprint requests
to Dr. Larsen at the Department of Human
Nutrition, Faculty of Life Sciences,
University of Copenhagen, Rolighedsvej 30,
1958 Frederiksberg, Copenhagen, Denmark,
or at tml@life.ku.dk.
N Engl J Med 2010;363:2102-13.
Copyright © 2010 Massachusetts Medical Society.
另外你們知道我們美安有一個醫生都來學習的學院叫 NutraMetrix 嗎?你們有上過她的網站嗎?原來她的內容好豐富呢！下面是有關Transitions的相關醫學研究文獻，大家亦可以email結朋友。
Weight Management– Selected References by title:
Low Glycemic:
Weight Loss, Body Measurement and Compliance – A 12-Week Total Lifestyle Intervention Pilot Study. Lieberman et al. Alt Comp Therapies. 2005;11:307-313.
Comparison of the Atkins, Ornish, Weight Watchers and Zone Diets for Weight Loss and Heart Disease Risk Reduction (A Randomized Trial). Dansinger, et al. JAMA. 2005; 293:43-53.
Systematic Review: An Evaluation of Major Commercial Weight Loss Programs in the US. Tsai and Wadden. Annals of Internal Medicine. 2005;56-66.
Long-Term Weight Loss Maintenance. Wing and Phelan. Am J Clin Nutr. 2005;222s-225s.
Why Do Obese Patients Not Lose More Weight When Treated with Low-Calorie Diets? Heymsfield et al. Am J Clin Nutr. 2007;346-354.
Should Obese Patients be Counseled to Follow a Low-Glycemic Index Diet? Yes. Pawlak et al. Obesity Reviews. 2002;3:235-243.
Comparison of 4 Diets of Varying Glycemic Load on Weight Loss and Cardiovascular Risk Reduction in Overweight and Obese Young Adults. McMillan-Price et al. Arch Int Med. 2006;1466-1475
Effects of a Low-Glycemic Load vs Low-Fat Diet in Obese Young Adults. Ebbeling et al. JAMA. 2007;297:2092-2102.
Effects of a Reduced GL Diet on Body Weight, Body Composition and CVD Risk Markers in Overweight and Obese Adults. Maki et al. Am J Clin Nutr. 2007; 85:724-734.
Meta-Analysis of the Health Effects of Using the Glycaemic Index in Meal Planning. Opperman et al. J. of Nutrition. 2004;367-381.
Effects of a Low-Glycemic Load Diet on Resting Energy Expenditure and Heart Disease Risk Factors During Weight Loss. Pereira et al. JAMA. 2004;2482-2490.
Influence of Glycemic Load on HDL Cholesterol in Youth. Slyper et al. Am J Clin Nutr. 2005; 81:376-379.
Effects of an Ad Libitum Low-GL Diet on Cardiovascular Disease Risk Factors in Obese Young Adults. Ebbeling et al. Am J Clin Nutr. 2005; 81:976-982.
Optimizing the Cardiovascular Outcomes of Weight Loss. Brand-Miller. Am J Clin Nutr. 2005; 81:949-950.
Strict Glycemic Control Ameliorates the Increase of Carotid IMT with Type 2 Diabetes. Kawasumi et al. Endocrine J. 2006;53:45-50.
Dietary Fiber Intake, Dietary Glycemic Load and the Risk for Gestational Diabetes. Zhang et al. Diabetes Care. 2006;29:2223-2230.
Effects of Breakfast Meal Composition on Second Meal Metabolic Responses in Adults with Type 2 Diabetes Mellitus. Clark et al. European J of Clin Nutr. 2006; 60:1122-1129.
GI, GL, and Cereal Fiber Intake and Risk of Type 2 Diabetes in US Black Women. Krishnan et al. Arch Int Med. 2007;167:2304-2309.
Prospective Study of Dietary Carbohydrates, GI, GL and Incidence of Type 2 Diabetes Mellitus in Middle-Aged Chinese Women. Villegas et al. Arch Int. Med. 2007;167:2310-2316.
Dietary Glycemic Index and Load, Measures of Glucose Metabolism, and Body Fat Distribution in Older Adults. Sahyoun et al. Am J Clin Nutr. 2005;82:547-552.
Putative Contributors to the Secular Increase in Obesity: Exploring the Roads Less Traveled. Keith et al. Int’l J of Obesity. 2006;30:1585-1594.
Effect of Alcoholic Beverages on Post-prandial Glycemia and Insulinemia in Lean, Young, Healthy Adults. Brand-Miller et al. Am J of Clin Nutr. 2007;85:1545-51.
Improved Weight Management Using Genetic Information to Personalize a Calorie Controlled Diet. Arkadianos et al. Nutrition Journal. 2007;6:29.
Source: www.nutrametrix.org/nei/references_wm.html
